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Hepatocytes, rather than leukocytes reverse DNA damage in vivo induced by whole body y-irradiation of mice, as shown by the alkaline comet assay

DNA damage repair was assessed in quiescent (G0) leukocytes and in hepatocytes of mice, after 1 and 2 hours recovery from a single whole body y-irradiation with 0.5, 1 or 2 Gy. Evaluation of single-strand breaks (SSB) and alkali-labile sites together were carried out by a single-cell electrophoresis...

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Detalhes bibliográficos
Principais autores: JUANA PINCHEIRA, PILAR CARRERA, KATHERINE MARCELAIN, CONSUELO DE LA TORRE
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2008-01-01
coleção:Biological Research
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Acesso em linha:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200011
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