Basophil Activation Test Predicts Cetuximab Anaphylaxis Severity in Alpha-Gal IgE-Positive Patients

Upon first exposure to cetuximab, hypersensitivity reactions can occur. We aimed to assess the utility of the basophil activation test (BAT) to alpha-gal and cetuximab for predicting severe reactions. We prospectively recruited 38 patients and evaluated sIgE to alpha-gal in all patients before the f...

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Bibliografische Detailangaben

Hauptverfasser:	Peter Kopač, Ana Koren, Urška Bidovec-Stojkovič, Mitja Košnik, Luka Dejanović, Tanja Mesti, Primož Strojan, Peter Korošec, Janja Ocvirk
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-07-01
Schriftenreihe:	Diagnostics
Schlagworte:	alpha-gal baseline serum tryptase basophil activation test cetuximab drug allergy
Online-Zugang:	https://www.mdpi.com/2075-4418/14/13/1403
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