Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis

Abstract Background Neoplastic invasion into leptomeninges and subarachnoid space, resulting in neoplastic meningitis (NM) is a fatal complication of advanced solid and hematological neoplasms. Identification of malignant involvement of the cerebrospinal fluid (CSF) early in the disease course has c...

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Autori principali:	Catharina Conrad, Kristina Dorzweiler, Miles A. Miller, Douglas A. Lauffenburger, Herwig Strik, Jörg W. Bartsch
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2017-08-01
Serie:	Fluids and Barriers of the CNS
Soggetti:	Neoplastic meningitis Metalloproteases CSF Real-time protease activities FRET-substrates
Accesso online:	http://link.springer.com/article/10.1186/s12987-017-0070-5
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