Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells

Abstract Background The efficiency and quality of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are crucial for regenerative medicine, disease modeling, drug screening, and the study of the development events during cardiac specification. However, their applications have bee...

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Detalhes bibliográficos

Principais autores:	Xiaowei Zhu, Suling Ding, Hui Li, Zhiwei Zhang, Lili Xu, Jian Wu, Xiangfei Wang, Yunzeng Zou, Xiangdong Yang, Junbo Ge
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-03-01
coleção:	Stem Cell Research & Therapy
Assuntos:	Human induced pluripotent stem cells Cardiac differentiation Histamine Histamine receptor
Acesso em linha:	http://link.springer.com/article/10.1186/s13287-020-1551-z
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