Matrix‐assisted Laser Desorption Ionization Mass Spectrometry for Detection of α/β‐Chain Changes From Human Hemoglobin: An Exploratory Study

ABSTRACT In this work, we developed a matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry (MALDI‐TOF‐MS) method to directly analyze human whole blood samples. 1.0 µL of whole blood samples and 1.0 µL of optimized organic matrix were directly loaded onto the sample plates for...

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Autors principals:	Dan‐ping Liu, Bi‐cheng Yang, Qiao‐yun Huang, Ping Liu, Hai‐yan Luo, Mao‐lin Yu, Jian‐qiong Yang, An Jia, Yan‐qiu Liu, Lin Xu, Bin Hu, Ting Huang
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley-VCH 2025-12-01
Col·lecció:	Analytical Science Advances
Matèries:	blood samples hemoglobin chain human hemoglobin mass spectrometry matrix‐assisted laser desorption ionization thalassemia
Accés en línia:	https://doi.org/10.1002/ansa.70037
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