Combining antigen-specific T cells with T-cell engager therapy induces a molecular signature that favors T-cell fitness

Abstract: Both adoptive cellular therapy with tumor antigen–specific T cells and redirection of endogenous T cells with bispecific tumor-specific T-cell engaging antibodies rely on CD8+ T cell effector function. The two approaches use complementary mechanisms of action (T-cell receptor [TCR]/major h...

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Bibliografiske detaljer

Principais autores:	Manpreet Bariana, Sidharth Anand, Mark Batistick, Elena Cassella, Shaina A. Anuncio, Ariel Aptekmann, David S. Siegel, Mathias Oelke, Sojung Kim, Ruipeng Wang, Jack A. Ragheb, Johannes L. Zakrzewski
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2025-06-01
Serier:	Blood Immunology & Cellular Therapy
Online adgang:	http://www.sciencedirect.com/science/article/pii/S3050597625000028
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