Intrahost Genetic Diversity of Dengue Virus in Human Hosts and Mosquito Vectors under Natural Conditions Which Impact Replicative Fitness <i>In Vitro</i>

Dengue virus (DENV) is an arbovirus whose transmission cycle involves disparate hosts: humans and mosquitoes. The error-prone nature of viral RNA replication drives the high mutation rates, and the consequently high genetic diversity affects viral fitness over this transmission cycle. A few studies...

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Autors principals:	Patcharaporn Nonyong, Tipaya Ekalaksananan, Supranee Phanthanawiboon, Hans J. Overgaard, Neal Alexander, Kesorn Thaewnongiew, Vorthon Sawaswong, Pattaraporn Nimsamer, Sunchai Payungporn, Juthamas Phadungsombat, Emi E. Nakayama, Tatsuo Shioda, Chamsai Pientong
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-04-01
Col·lecció:	Viruses
Matèries:	dengue virus <i>Aedes aegypti</i> intrahost genetic diversity selection pressure host switching replication kinetics
Accés en línia:	https://www.mdpi.com/1999-4915/15/4/982
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