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Regulation of PCNA polyubiquitination in human cells

<p>Abstract</p> <p>Background</p> <p>The ubiquitin-based molecular switch dictating error free versus error prone repair has been conserved throughout eukaryotic evolution. A central component of this switch is the homotrimeric clamp PCNA, which is ubiquitinated in response to genotoxic stress allow...

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Bibliografische Detailangaben
Hauptverfasser: Chiu Roland K, Brun Jan, Wouters Bradly G, Gray Douglas A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2010-03-01
Schriftenreihe:BMC Research Notes
Online-Zugang:http://www.biomedcentral.com/1756-0500/3/85
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