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ICDM-GEHC: identifying cancer driver module based on graph embedding and hierarchical clustering

Abstract Due to the high heterogeneity of cancers, it is rather essential to explore driver modules with the help of gene mutation data as well as known interactions between genes/proteins. Unfortunately, latent false positive interactions are inevitable in the Protein-Protein Interaction (PPI) netw...

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Main Authors: Shiyu Deng, Jingli Wu, Gaoshi Li, Jiafei Liu, Yumeng Zhao
Format: Artigo
Language:Inglês
Published: Springer 2024-02-01
Series:Complex & Intelligent Systems
Subjects:
Cancer driver module
Graph embedding
Multi-omics
Hierarchical clustering
Online Access:https://doi.org/10.1007/s40747-023-01328-5
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