Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945

Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker. Here, we explored the impact of CK2 inhibition over the phosph...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Mauro Rosales, Arielis Rodríguez-Ulloa, Vladimir Besada, Ailyn C. Ramón, George V. Pérez, Yassel Ramos, Osmany Guirola, Luis J. González, Katharina Zettl, Jacek R. Wiśniewski, Yasser Perera, Silvio E. Perea
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-02-01
Schriftenreihe:	Cells
Schlagworte:	phosphoproteomics casein kinase 2 kinase inhibitor CX-4945 acute myeloid leukemia
Online-Zugang:	https://www.mdpi.com/2073-4409/10/2/338
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