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STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis

Background and objectives Acute kidney injury (AKI) is one of the most common and severe clinical syndromes of diffuse proliferative lupus nephritis (DPLN), of which poor prognosis is indicated by aggravated renal function deterioration. However, the specific therapy and mechanisms of AKI in DPLN re...

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Principais autores: Jianfen Zhu, Yijing Chen, Yulan Chen, Yinqiu Lv, Tianxin Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Renal Failure
Assuntos:
STAT3
AKI
lupus nephritis
renal interstitial
Acesso em linha:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2358187
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