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The present status of metformin in fertility-preserving treatment in atypical endometrial hyperplasia and endometrioid endometrial cancer

Progestin therapy is the main fertility-sparing treatment for women with endometrial cancer (EC) and atypical endometrial hyperplasia (AEH). However, still 15-25% of these women failed to achieve complete response (CR) and then lost their fertility after definitive surgery. Metformin has been demons...

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Detalles Bibliográficos
Principais autores: Jun Guan, Xiao-Jun Chen
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fendo.2022.1041535/full
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