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Landscape and regulation of mRNA translation in the early C. elegans embryo

Summary: Animal embryos rely on regulated translation of maternally deposited mRNAs to drive early development. Using low-input ribosome profiling combined with RNA sequencing on precisely staged embryos, we measure mRNA translation during the first four cell cycles of C. elegans development. We unc...

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Principais autores: Yash Shukla, Vighnesh Ghatpande, Cindy F. Hu, Daniel J. Dickinson, Can Cenik
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2025-06-01
Serija:Cell Reports
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2211124725005492
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