Optimization of plasma-based BioID identifies plasminogen as a ligand of ADAMTS13

Abstract ADAMTS13, a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13, regulates the length of Von Willebrand factor (VWF) multimers and their platelet-binding activity. ADAMTS13 is constitutively secreted as an active protease and is not inhibited by circulating proteas...

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Bibliografiske detaljer

Principais autores:	Hasam Madarati, Veronica DeYoung, Kanwal Singh, Taylor Sparring, Andrew C. Kwong, James C. Fredenburgh, Cherie Teney, Marlys L. Koschinsky, Michael B. Boffa, Jeffrey I. Weitz, Colin A. Kretz
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2024-04-01
Serier:	Scientific Reports
Fag:	ADAMTS13 BioID Plasminogen Von Willebrand factor
Online adgang:	https://doi.org/10.1038/s41598-024-59672-6
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