Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy

Context Panax japonicus is the dried rhizome of Panax japonicus C.A. Mey. (Araliaceae). Saponins from Panax japonicus (SPJ) exhibit anti-inflammatory and antioxidative effects. Objective To explore the neuroprotective effect of SPJ on natural ageing of rat. Materials and methods Sprague-Dawley (SD)...

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Detalhes bibliográficos

Principais autores:	Xue-Jiao Pi, Qing-Qing Zhao, Jin-Xin Wang, Xu-Lan Zhang, Ding Yuan, Shan-Shan Hu, Yu-Min He, Chang-Cheng Zhang, Zhi-Yong Zhou, Ting Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2021-01-01
coleção:	Pharmaceutical Biology
Assuntos:	neuroinflamamtion cognitive function microglia m1-like phenotype m2-like phenotype
Acesso em linha:	http://dx.doi.org/10.1080/13880209.2021.1961824
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