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Identification of HLA-DRPheβ47 as the susceptibility marker of hypersensitivity to beryllium in individuals lacking the berylliosis-associated supratypic marker HLA-DPGluβ69

<p>Abstract</p> <p>Background</p> <p>Susceptibility to beryllium (Be)-hypersensitivity (BH) has been associated with HLA-DP alleles carrying a glutamate at position 69 of the HLA-DP β-chain (HLA-DPGlu69) and with several HLA-DP, -DQ and -DR alleles and polymorphisms. However, no genetic associations...

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Principais autores: Rogliani Paola, Butler Richard H, Rossman Milton, Berretta Floriana, Amicosante Massimo, van den Berg-Loonen Ella, Saltini Cesare
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2005-08-01
Serier:Respiratory Research
Online adgang:http://respiratory-research.com/content/6/1/94
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