Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells

<p>Abstract</p> <p>Background</p> <p>The Shc isoforms is known to mediate immune responses and has been indicated as a negative regulator of autoimmunity and lymphocyte activation. We aimed to evaluate the immune-regulatory role of Shc in rat bone marrow-derived DCs in the maturation process trigger...

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Principais autores:	Cheng Yu-Fan, Wang Chih-Chi, Hou Chiung-Hui, Chang Yen-Chen, Lai Chia-Yun, Nakano Toshiaki, Yeh Chin-Wei, Goto Shigeru, Hsu Li-Wen, Chen Kuang-Den, Chiu King-Wah, Lin Chih-Che, Chen Chao-Long
格式:	Artigo
語言:	Inglês
出版:	BMC 2011-05-01
叢編:	BMC Immunology
在線閱讀:	http://www.biomedcentral.com/1471-2172/12/32
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