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The endocannabinoid system is modulated in response to spinal cord injury in rats

Endocannabinoids are lipid mediators with protective effects in many diseases of the nervous system. We have studied the modulation of the endocannabinoid system after a spinal cord contusion in rats. In early stages, lesion induced increases of anandamide and palmitoylethanolamide (PEA) levels, an...

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Principais autores: Daniel Garcia-Ovejero, Angel Arevalo-Martin, Stefania Petrosino, Fabian Docagne, Carlos Hagen, Tiziana Bisogno, Masahiko Watanabe, Carmen Guaza, Vincenzo Di Marzo, Eduardo Molina-Holgado
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2009-01-01
coleção:Neurobiology of Disease
Assuntos:
Diacylglycerol lipase
Injury
Cannabinoids
CB1
CB2
Palmitoylethanolamide
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0969996108002258
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