VacA’s Induction of VacA-Containing Vacuoles (VCVs) and Their Immunomodulatory Activities on Human T Cells

Vacuolating cytotoxin A (VacA) is a secreted pore-forming toxin and one of the major virulence factors of Helicobacter pylori (H. pylori), which actively supports the persistence and survival of the bacteria in the special ecological niche of the human stomach. H. pylori genomes harbor different all...

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Bibliografische Detailangaben

Hauptverfasser:	Ciara Utsch, Rainer Haas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2016-06-01
Schriftenreihe:	Toxins
Schlagworte:	cell vacuolation VacA channel protein-protein interaction apoptosis IL-2 secretion proliferation inhibition vesicle transport
Online-Zugang:	http://www.mdpi.com/2072-6651/8/6/190
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