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TNFR2 Costimulation Differentially Impacts Regulatory and Conventional CD4+ T-Cell Metabolism

CD4+ conventional T cells (Tconvs) mediate adaptive immune responses, whereas regulatory T cells (Tregs) suppress those responses to safeguard the body from autoimmunity and inflammatory diseases. The opposing activities of Tconvs and Tregs depend on the stage of the immune response and their enviro...

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Autori principali: Mark Mensink, Thi Ngoc Minh Tran, Esther A. Zaal, Ellen Schrama, Celia R. Berkers, Jannie Borst, Sander de Kivit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-06-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2022.881166/full
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