Trk Inhibition Reduces Tumorsphere Formation and Changes Expression of Stemness Markers in SK-ES-1 Ewing Sarcoma Cells

Introduction: Ewing sarcoma (ES) is a highly aggressive type of childhood cancer characterized by a chromosomal translocation resulting in fusions between the gene encoding EWS RNA Binding Protein 1 (EWSR1) and one gene of the ETS family, most frequently FLI-1, resulting in the EWS-FLI1 aberrant tr...

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Bibliographic Details

Main Authors:	Rafael Pereira dos Santos, Bruna Almeida dos Santos, Lauro Gregianin, André Tessainer Brunetto, Algemir Lunardi Brunetto, Rafael Roesler, Caroline Brunetto de Farias
Format:	Artigo
Language:	Inglês
Published:	Instituto Nacional de Câncer (INCA) 2024-01-01
Series:	Revista Brasileira de Cancerologia
Subjects:	Receptor, trkA receptors, nerve growth factor neoplastic stem cells sarcoma, Ewing
Online Access:	https://rbc.inca.gov.br/index.php/revista/article/view/4262
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