Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis

Abstract Background Satellite cells (SCs) are critical to skeletal muscle regeneration. Inactivation of SCs is linked to skeletal muscle loss. Transferrin receptor 1 (Tfr1) is associated with muscular dysfunction as muscle‐specific deletion of Tfr1 results in growth retardation, metabolic disorder,...

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Detalhes bibliográficos

Principais autores:	Hongrong Ding, Shujie Chen, Xiaohan Pan, Xiaoshuang Dai, Guihua Pan, Ze Li, Xudong Mai, Ye Tian, Susu Zhang, Bingdong Liu, Guangchao Cao, Zhicheng Yao, Xiangping Yao, Liang Gao, Li Yang, Xiaoyan Chen, Jia Sun, Hong Chen, Mulan Han, Yulong Yin, Guohuan Xu, Huijun Li, Weidong Wu, Zheng Chen, Jingchao Lin, Liping Xiang, Jun Hu, Yan Lu, Xiao Zhu, Liwei Xie
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2021-06-01
coleção:	Journal of Cachexia, Sarcopenia and Muscle
Assuntos:	Tfr1 Satellite cells Ferroptosis Fibro/adipogenic progenitors
Acesso em linha:	https://doi.org/10.1002/jcsm.12700
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