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Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation

ABSTRACT The Epstein-Barr virus (EBV) is a human gamma-herpesvirus which infects over 90% of the global population and is associated with lymphoid and epithelioid cancers. After infection, EBV enters a latent state in B cells, whereby the viral genome persists as a nuclear episome maintained by expr...

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Principais autores: Daniel E. Greaves, Ildar Gabaev, James C. Williamson, Stuart Bloor, Sergio Martinez Cuesta, Nicholas J. Matheson, Lori Frappier, Jérôme Déjardin, Paul J. Lehner
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2026-04-01
Serier:Journal of Virology
Fag:
Epstein-Barr virus
locus specific proteomics
epigenetics
virus latency
virus activation
Polycomb complex
Online adgang:https://journals.asm.org/doi/10.1128/jvi.01408-25
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