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Applying an empirical hydropathic forcefield in refinement may improve low-resolution protein X-ray crystal structures.

The quality of X-ray crystallographic models for biomacromolecules refined from data obtained at high-resolution is assured by the data itself. However, at low-resolution, >3.0 Å, additional information is supplied by a forcefield coupled with an associated refinement protocol. These resulting struc...

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Váldodahkkit: Vishal N Koparde, J Neel Scarsdale, Glen E Kellogg
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2011-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3016398?pdf=render
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