Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

The complement system consists of effector proteins, regulators, and receptors that participate in host defense against pathogens. Activation of the complement system, via the classical pathway (CP), has long been recognized in immune complex-mediated tissue injury, most notably systemic lupus eryth...

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Auteurs principaux:	Katherine eLintner, Yee Ling eWu, Yan eYang, Charles eSpencer, Georges eHauptmann, Lee eHebert, John eAtkinson, Chack-Yung eYu
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2016-02-01
Collection:	Frontiers in Immunology
Sujets:	Autoimmune Diseases Complement C1q Complement C1r Complement C1s Complement C2 Complement C4
Accès en ligne:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00036/full
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