Revealing the location and dynamics of a concealed binding site in the dopamine transporter

Abstract The dopamine transporter (DAT) is linked to neuropsychiatric disorders including ADHD, Parkinson’s disease, and substance use disorders. Accordingly, DAT is the target of illicit drugs and clinically important medicines. However, the number and function of ligand binding sites in DAT is eni...

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Үндсэн зохиолчид:	Rong Zhu, Walter Sandtner, Thomas Stockner, Alexander Heilinger, Marion Holy, Oliver Kudlacek, Linda Wildling, Kusumika Saha, Anna Sophie Fröhlich, Michael Bindl, Paraskevi Tziortzouda, Anna Haider, Julia Gobl, Saanfor Hubert Suh, Jawad Akbar Khan, Julia Bicher, Nina Kastner, Andreas Ebner, Hermann J. Gruber, Michael Freissmuth, Amy Hauck Newman, Harald H. Sitte, Peter Hinterdorfer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-05-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-025-59511-w
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!