Mutations in <it>ASXL1 </it>are associated with poor prognosis across the spectrum of malignant myeloid diseases
<p>Abstract</p> <p>The <it>ASXL1 </it>gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic regulation of gene expression. <it>ASXL1 </it>mutations are found in myeloproliferative neoplasms (MPN), mye...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMC
2012-03-01
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| Series: | Journal of Hematology & Oncology |
| Subjects: | |
| Online Access: | http://www.jhoonline.org/content/5/1/12 |
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