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Circulating mucosal-like IgA responses increase with severity of Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome

Old World Orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by increased vascular permeability and acute kidney injury (AKI). Despite the systemic nature of the disease, the virus enters humans through inhalation and therefore initially encounters the immunoglobulin...

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Autors principals: Luz E. Cabrera, Cienna Buckner, Veronica Then, Sanna Mäki, Olli Vapalahti, Antti Vaheri, Jussi Hepojoki, Johanna Tietäväinen, Satu Mäkelä, Jukka Mustonen, Tomas Strandin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-10-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1480041/full
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