Overexpression of ASvicR combined with the antibacterial monomer DMAHDM interferes with the VicRK two-component system to attenuate the cariogenicity of Streptococcus mutans

BackgroundStreptococcus mutans (S. mutans) is a primary cariogenic pathogen responsible for acid production, exopolysaccharides (EPS) production and biofilm formation. Two-component systems (TCS) regulate EPS metabolism, especially the VicRK TCS. Overexpression of antisense vicR (ASvicR) can reduce...

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Үндсэн зохиолчид:	Yuting Sun, Han Du, Xuele Pan, Zheng Wang, Xinyi Zhang, Ruiqi Yang, Hong Chen, Deqin Yang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-03-01
Цуврал:	Frontiers in Cellular and Infection Microbiology
Нөхцлүүд:	antisense vicR (ASvicR) cariogenicity dimethylaminohexadecylmethacrylate (DMAHDM) Streptococcus mutans VicRK TCS
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fcimb.2026.1793140/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!