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Recombinant Type XVII Collagen Inhibits EGFR/MAPK/AP-1 and Activates TGF-β/Smad Signaling to Enhance Collagen Secretion and Reduce Photoaging

Studies have consistently shown that long-wave ultraviolet A (UVA) radiation triggers skin photoaging, which is evident as reduced elasticity, a loss of firmness, and signs of aging. There is an urgent need to investigate photoaging mechanisms to devise protective strategies against UVA. The present...

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Principais autores: Ying He, Shiyu Yin, Ru Xu, Yan Zhao, Yuhang Du, Zhiguang Duan, Daidi Fan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-03-01
Serier:Cosmetics
Fag:
recombinant collagen XVII
EGFR
MAPK
photoaging
basement membrane proteins
Online adgang:https://www.mdpi.com/2079-9284/12/2/59
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