Evaluation of nanoparticle albumin-bound paclitaxel loaded macrophages for glioblastoma treatment based on a microfluidic chip

Introduction: Glioblastoma (GBM) is a primary brain malignancy with a dismal prognosis and remains incurable at present. In this study, macrophages (MΦ) were developed to carry nanoparticle albumin-bound paclitaxel (nab-PTX) to form nab-PTX/MΦ. The aim of this study is to use a GBM-on-a-chip to eval...

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Principais autores:	Zuorun Xie, Junyi Ye, Xinghua Gao, Hang Chen, Maosong Chen, Jiangfang Lian, Jingyun Ma, Hongcai Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-03-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	microfluidic chip glioblastoma macrophage-based carrier drug delivery nanoparticle albumin-bound paclitaxel
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2024.1361682/full
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