PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity

Abstract Diabetes is a multi‐organ disease and diabetic cardiomyopathy can result in heart failure, which is a leading cause of morbidity and mortality in diabetic patients. In the liver, insulin resistance contributes to hyperglycaemia and hyperlipidaemia, which further worsens the metabolic profil...

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Detalhes bibliográficos

Principais autores:	Mirko Völkers, Shirin Doroudgar, Nathalie Nguyen, Mathias H Konstandin, Pearl Quijada, Shabana Din, Luis Ornelas, Donna J Thuerauf, Natalie Gude, Kilian Friedrich, Stephan Herzig, Christopher C Glembotski, Mark A Sussman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer Nature 2013-10-01
coleção:	EMBO Molecular Medicine
Assuntos:	diabetes PRAS40 mTOR
Acesso em linha:	https://doi.org/10.1002/emmm.201303183
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