MAPK Pathway Activation Patterns in the Synovium Reveal ERK1/2 and EGFR as Key Players in Osteoarthritis

<b>Background/Objectives</b>: Chronic synovitis is a hallmark of osteoarthritis (OA) progression, driving cartilage degradation via inflammatory mediators. While the MAPK signaling pathway is implicated in OA pathogenesis its activation patterns in hip synovium remain poorly characterized, and regio...

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Autors principals:	Ivana Jurić, Petar Todorović, Nela Kelam, Danica Boban, Patricija Bajt, Anita Racetin, Matko Rošin, Davor Čarić, Katarina Vukojević
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-12-01
Col·lecció:	Biomedicines
Matèries:	osteoarthritis synovial membrane ERK 1/2 p38 JNK EGFR
Accés en línia:	https://www.mdpi.com/2227-9059/13/12/2992
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