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Control of human β-globin mRNA stability and its impact on beta-thalassemia phenotype

Messenger RNA (mRNA) stability is a critical determinant that affects gene expression. Many pathways have evolved to modulate mRNA stability in response to developmental, physiological and/or environmental stimuli. Eukaryotic mRNAs have a considerable range of half-lives, from as short as a few minu...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Isabel Peixeiro, Ana Luísa Silva, Luísa Romão
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2011-06-01
Schriftenreihe:Haematologica
Online-Zugang:https://haematologica.org/article/view/5998
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