Impact of MEFV mutations on inflammatory activity and long-term relapse in pediatric IgA vasculitis

Abstract Background IgA vasculitis (IgAV) is the most common childhood small-vessel vasculitis. MEFV variants may enhance innate inflammatory responses, but their effect on disease course remains unclear. Objectives To determine the prevalence of MEFV mutations in pediatric IgAV and evaluate associa...

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Bibliografische Detailangaben

Hauptverfasser:	Göktuğ Özdemir, Esma Kaya Özdemir, Asım Gültekin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-02-01
Schriftenreihe:	BMC Pediatrics
Schlagworte:	IgA vasculitis Henoch–Schönlein purpura MEFV Relapse Inflammation
Online-Zugang:	https://doi.org/10.1186/s12887-026-06664-2
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