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Extracellular vesicles derived from dental mesenchymal stem/stromal cells with gemcitabine as a cargo have an inhibitory effect on the growth of pancreatic carcinoma cell lines in vitro

Extracellular vesicles (EVs) are nowadays a target of interest in cancer therapy as a successful drug delivering tool. Based on their many beneficial biocompatible properties are designed to transport nucleic acids, proteins, various nanomaterials or chemotherapeutics. Extracellular vesicles derived...

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Principais autores: Daniela Klimova, Jana Jakubechova, Ursula Altanerova, Andreas Nicodemou, Jakub Styk, Tomas Szemes, Vanda Repiska, Cestmir Altaner
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-02-01
Serier:Molecular and Cellular Probes
Fag:
Dental mesenchymal stem/stromal cells
Extracellular vesicles
Gemcitabine
Suicide gene
5-Fluorocytosine
5-Fluorouracil
Online adgang:http://www.sciencedirect.com/science/article/pii/S0890850823000038
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