Identification of organs of origin of macrophages that produce presepsin via neutrophil extracellular trap phagocytosis

Abstract Presepsin (P-SEP) is a specific biomarker for sepsis. Monocytes produce P-SEP by phagocytosing neutrophil extracellular traps (NETs). Herein, we investigated whether M1 macrophages (M1 MΦs) are the primary producers of P-SEP after NET phagocytosis. We co-cultured M1 MΦs and NETs from health...

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Bibliografische Detailangaben

Hauptverfasser:	Akihiro Kondo, Tatsuya Morinishi, Yusuke Yamaguchi, Akishige Ikegame
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2024-07-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Presepsin Macrophage Neutrophil extracellular traps Sepsis Biomarker
Online-Zugang:	https://doi.org/10.1038/s41598-024-66916-y
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