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Rho GTPase and Rho Kinase Signaling in Tissue Contractility and Intraocular Pressure Regulation

The Rho GTPase and Rho kinase (ROCK) signaling pathway is essential for cellular mechanics, acting as key regulators of the actin cytoskeleton and actomyosin contractility in various cell types and tissues. Rho GTPases, functioning as molecular switches, and ROCKs, their primary downstream effectors...

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Principais autores: Srimathi Raghavan, Padmanabhan P Pattabiraman
Format: Artigo
Sprog:Inglês
Udgivet: IMR Press 2026-01-01
Serier:Frontiers in Bioscience-Landmark
Fag:
rho gtp-binding proteins
rho-associated kinases
actin cytoskeleton
extracellular matrix
trabecular meshwork
glaucoma
intraocular pressure
Online adgang:https://www.imrpress.com/journal/FBL/31/1/10.31083/FBL44589
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