Design and Synthesis of Helical <i>N</i>-Terminal <span style="font-variant: small-caps">l</span>-Prolyl Oligopeptides Possessing Hydrocarbon Stapling

We designed and synthesized helical short oligopeptides with an <span style="font-variant: small-caps;">l</span>-proline on the N-terminus and hydrocarbon stapling on the side chain. Side-chain stapling is a frequently used method for the development of biologically active peptides. Side-chain stapl...

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Principais autores:	Atsushi Ueda, Mei Higuchi, Kazuki Sato, Tomohiro Umeno, Masakazu Tanaka
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-10-01
coleção:	Molecules
Assuntos:	peptide helix hydrocarbon stapling ring-closing metathesis organocatalyst <span style="font-variant: small-caps">l</span>-proline
Acesso em linha:	https://www.mdpi.com/1420-3049/25/20/4667
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