DNA Damage Clustering after Ionizing Radiation and Consequences in the Processing of Chromatin Breaks

Charged-particle radiotherapy (CPRT) utilizing low and high linear energy transfer (low-/high-LET) ionizing radiation (IR) is a promising cancer treatment modality having unique physical energy deposition properties. CPRT enables focused delivery of a desired dose to the tumor, thus achieving a bett...

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Hauptverfasser:	Veronika Mladenova, Emil Mladenov, Martin Stuschke, George Iliakis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-02-01
Schriftenreihe:	Molecules
Schlagworte:	ionizing radiation high-LET ionizing radiation charged-particle radiotherapy double-strand breaks DNA damage response complex double-strand breaks
Online-Zugang:	https://www.mdpi.com/1420-3049/27/5/1540
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