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Metabolomic profiling reveals alterations in Candida pathophysiology and host interactions during primary oral candidiasis and following antifungal treatment

Abstract Comparative metabolomics may shed light on host immunity and biology in oral candidiasis (oral thrush). Untargeted metabolomic analyses were performed on oral rinses collected from 26 primary oral candidiasis patients (OT), 12 patients after antifungal treatment (AT), and 12 unaffected indi...

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Sábháilte in:
Príomhchruthaitheoirí: Nuramirah Azizan, Anis Rageh Al-Maleki, Mohd Salleh Rofiee, Alexandria Sonia Karajacob, Mun Fai Loke, Joanne Pei En Goh, Thomas George Kallarakkal, Wan Himratul Aznita Wan Harun, Rathna Devi Vaithilingam, Lay Kek Teh, Mohd Zaki Salleh, Sun Tee Tay
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2026-01-01
Sraith:Scientific Reports
Ábhair:
Metabolomics
Oral metabolites
Primary oral candidiasis
Oral rinse
Antifungal
Rochtain ar líne:https://doi.org/10.1038/s41598-025-29629-4
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