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Effect of spin labelling on the aggregation kinetics of yeast prion protein Ure2

Amyloid formation is involved in a wide range of neurodegenerative diseases including Alzheimer's and prion diseases. Structural understanding of the amyloid is critical to delineate the mechanism of aggregation and its pathological spreading. Site-directed spin labelling has emerged as a powerful s...

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Autori principali: Emilie N. Liu, Giovanna Park, Junsuke Nohara, Zhefeng Guo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2021-03-01
Serie:Royal Society Open Science
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Accesso online:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.201747
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