No evidence of neuronal damage as measured by neurofilament light chain in a HIV cure study utilising a kick-and-kill approach

Objective: HIV-remission strategies including kick-and-kill could induce viral transcription and immune-activation in the central nervous system, potentially causing neuronal injury. We investigated the impact of kick-and-kill on plasma neurofilament light (NfL), a marker of neuro-axonal injury, in...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Jasmini Alagaratnam, Wolfgang Stöhr, Jamie Toombs, Amanda Heslegrave, Henrik Zetterberg, Magnus Gisslén, Sarah Pett, Mark Nelson, Amanda Clarke, Nneka Nwokolo, Margaret A. Johnson, Maryam Khan, Tomas Hanke, Jakub Kopycinski, Lucy Dorrell, Julie Fox, Sabine Kinloch, Jonathan Underwood, Matthew Pace, John Frater, Alan Winston, Sarah Fidler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-09-01
coleção:	Journal of Virus Eradication
Assuntos:	Neurofilament light chain protein Neuro-axonal injury Vorinostat HIV-1 therapeutic vaccination HIV-1 remission approach Kick and kill
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2055664021000297
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!