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Pathophysiological Roles of the TRPV4 Channel in the Heart

The transient receptor potential vanilloid 4 (TRPV4) channel is a non-selective cation channel that is mostly permeable to calcium (Ca<sup>2+</sup>), which participates in intracellular Ca<sup>2+</sup> handling in cardiac cells. It is widely expressed through the body and is activated by a large spe...

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Principais autores: Sébastien Chaigne, Solène Barbeau, Thomas Ducret, Romain Guinamard, David Benoist
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-06-01
Serier:Cells
Fag:
TRPV4 channels
TRPV4-KO mice
heart
myocytes
fibroblasts
endothelial cells
Online adgang:https://www.mdpi.com/2073-4409/12/12/1654
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