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Clorgyline Analogs Synergize with Azoles against Drug Efflux in <i>Candida auris</i>

Concern about the global emergence of multidrug-resistant fungal pathogens led us to explore the use of combination therapy to combat azole resistance in <i>Candida auris</i>. Clorgyline had previously been shown to be a multi-target inhibitor of Cdr1 and Mdr1 efflux pumps of <i>Candida albicans</i>...

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Hauptverfasser: Stephanie Toepfer, Michaela Lackner, Mikhail V. Keniya, Lisa-Maria Zenz, Marianne Friemert, Franz Bracher, Brian C. Monk
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-06-01
Schriftenreihe:Journal of Fungi
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Online-Zugang:https://www.mdpi.com/2309-608X/9/6/663
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