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Optimization of protein extraction and digestion workflows for proteomic analysis of saliva, salivary stones and kidney stones

BackgroundSalivary and kidney stone diseases are associated with pathological calcification, yet their molecular composition remains incompletely characterized. Proteomic analysis of saliva and stone material may provide valuable insights into these processes; however, such analyses are technically...

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Principais autores: Natalia Musiał, Martyna Iwaniec, Inez Mruk, Michał Puchalski, Dmitry Tretiakow, Andrzej Skorek, Konrad Szydłowski, Jan Szlęzak, Paulina Czaplewska
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-03-01
coleção:Frontiers in Molecular Biosciences
Assuntos:
biocalcification
biomarkers
kidney stones
proteomics
saliva
salivary stones
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmolb.2026.1769952/full
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