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HS1 deficiency protects against sepsis by attenuating neutrophil-inflicted lung damage

Sepsis remains an important health problem worldwide due to inefficient treatments often resulting in multi-organ failure. Neutrophil recruitment is critical during sepsis. While neutrophils are required to combat invading bacteria, excessive neutrophil recruitment contributes to tissue damage due t...

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Principais autores: Idaira M. Guerrero-Fonseca, Alexander García-Ponce, Eduardo Vadillo, Nathaniel L. Lartey, Hilda Vargas-Robles, Sandra Chánez-Paredes, Ramón Castellanos-Martínez, Porfirio Nava, Abigail Betanzos, Brittany M. Neumann, Kinga Penkala-Auguste, Craig T. Lefort, Michael Schnoor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-04-01
Colecção:European Journal of Cell Biology
Assuntos:
Inflammation
HCLS
Cortactin
Diapedesis
Neutrophil extravasation
Actin dynamics
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0171933522000176
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