Low human dystrophin levels prevent cardiac electrophysiological and structural remodelling in a Duchenne mouse model

Abstract Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder caused by loss of dystrophin. This lack also affects cardiac structure and function, and cardiovascular complications are a major cause of death in DMD. Newly developed therapies partially restore dystrophin expressio...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Gerard A. Marchal, Maaike van Putten, Arie O. Verkerk, Simona Casini, Kayleigh Putker, Shirley C. M. van Amersfoorth, Annemieke Aartsma-Rus, Elisabeth M. Lodder, Carol Ann Remme
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-05-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-89208-1
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!