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Old dogs-new tricks: multifaceted functions of MAVS beyond antivirus activity in human health and diseases

Abstract Mitochondrial Antiviral Signaling Protein (MAVS), a key adaptor in the innate immune system, has traditionally been recognized for its role in defending against viral infections through activation of the interferon (IFN) and NF-κB signaling pathways. Recent studies, however, have expanded t...

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Principais autores: Yating Lu, Yaxuan Qi, Qingqing Yinliang, Rui Zhu, Alexey Sarapultsev, Shanshan Luo, Jing Cui, Desheng Hu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:Cell & Bioscience
Fag:
MAVS
Innate immunity
Mitochondria
Human disease
Therapeutics
Online adgang:https://doi.org/10.1186/s13578-025-01512-9
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