A versatile, fast and unbiased method for estimation of gene-by-environment interaction effects on biobank-scale datasets

Abstract Identification of gene-by-environment interactions (GxE) is crucial to understand the interplay of environmental effects on complex traits. However, current methods evaluating GxE on biobank-scale datasets have limitations. We introduce MonsterLM, a multiple linear regression method that do...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Matteo Di Scipio, Mohammad Khan, Shihong Mao, Michael Chong, Conor Judge, Nazia Pathan, Nicolas Perrot, Walter Nelson, Ricky Lali, Shuang Di, Robert Morton, Jeremy Petch, Guillaume Paré
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2023-08-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-023-40913-7
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!